Indeed tier assemblies is a cool NDepeni features I descaibed in depth here: Controlling the usage of Library
> the several hundred DataSet assemblies reared their ugly heads again and utterly crushed NDepend with the weight of all their fatty members.
Our goal achieved with NDepend v3, was to be able to analyze the whole .NET Fx assemblies on a 32 bits machine in less than a minute. This represents around 1.5M Lines of Code. So with your datasets assemblies, your app seems to be bigger than the whole .NET Fx. You can buy a 64bits machine :)